Publications by authors named "S V Eleswarapu"
Male infertility has been a primary cause of global infertility, affecting 8-12% of couples worldwide. Previous studies have shown that semen quality decreases with advanced aging with an increased presence of inflammatory cells. In this study, we examined changes in the epigenome across a diverse cohort that includes both fertile and infertile men.
View Article and Find Full Text PDFBackground: A varicocele is an abnormal dilation of the pampiniform plexus of veins in the scrotum that commonly affects postpubertal males. The condition has been associated with male infertility, testicular hypotrophy, and pain. However, the clinical experiences of adolescent patients and their families regarding the evaluation, surveillance, and management of varicoceles have not been previously examined.
View Article and Find Full Text PDFArticle Synopsis
- Varicoceles are a common issue affecting up to 30% of adolescent males, but researching this topic is challenging due to its sensitive nature.
- This study utilized social media, specifically the Reddit forum "r/varicocele," and employed natural language processing (NLP) techniques to analyze the discussions of young males about their condition.
- The findings highlighted key themes from 1103 posts, including general information about varicoceles, management strategies, post-treatment experiences, community support, and the need for second opinions from physicians, with specific concerns about hypogonadism and semen analysis also noted.
Article Synopsis
- - The review examines the growing interest in using artificial intelligence (AI) to improve clinical decision-making for Peyronie's disease (PD) evaluations.
- - Advances in 3D modeling are promising for better assessing PD deformities, but challenges like needing specialized equipment and lengthy data processing still hinder its clinical use.
- - There's potential for AI to streamline these processes and enhance clinical outcomes, but more research is required to prove it's better than traditional diagnostic methods.
Background And Objective: Time to testosterone recovery (TR) following androgen deprivation therapy (ADT) with gonadotropin-releasing hormone agonists varies widely. We evaluate TR kinetics and the oncological impact of an effective castration period in patients receiving definitive radiotherapy and ADT for prostate cancer.
Methods: We obtained individual patient data from randomized controlled trials of radiotherapy with ADT and prospectively collected serial testosterone data from the MARCAP Consortium.