Publications by authors named "S V Dholakia"

Article Synopsis
  • The study explores a new diagnostic approach for empty nose syndrome (ENS) using a four-part Stepwise Empty Nose Syndrome Evaluation (SENSE) cotton test, which improves upon the traditional single-step cotton test to minimize bias and assess the placebo effect.
  • In the SENSE test, patients undergo various cotton placement scenarios while completing the ENS6Q questionnaire, revealing that many experience significant placebo effects and varying responses to different cotton placements.
  • Results showed that while a majority of ENS patients preferred any form of cotton placement for nasal relief, they could still detect subtle differences in their breathing experience, emphasizing the need to consider individual responses in treatment.
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Objectives: Behavioral and psychological symptoms of dementia (BPSD) are common and impart a significant burden to patients, caregivers, and the health system. However, there are few pharmacological options for treating BPSD. We conducted a systematic review of clinical trials examining the efficacy of anticonvulsants in BPSD.

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Malaria caused by P. falciparum, has been recognized as one of the major infectious diseases causing the death of several patients as per the reports from the World Health Organization. In search of effective therapeutic agents against malaria, several research groups have started working on the design and development of novel heterocycles as anti-malarial agents.

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Article Synopsis
  • Dimenhydrinate is an over-the-counter medication used to treat nausea and motion sickness, but chronic high-dose use may lead to cognitive issues, particularly concerning dementia.
  • A case study details a woman in her 40s who abused dimenhydrinate daily and developed a minor neurocognitive disorder along with delusional beliefs, although other health conditions and lifestyle factors also played a role.
  • This report highlights increasing concerns about long-term cognitive effects of anticholinergic medications, which were previously thought to primarily affect older adults.
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