[Changes of peritumoral testicular tissue in patients with germ cell tumors].

For the purpose of definition of characteristic morphological changes of testicular tissue which to be surveyed as precancerous, the peritumoral tissue at 40 patients with testicular germ cell tumors (TGCT) which has been spent orchiectomy is investigated and the diagnosis according to classification TNM is established. In peritumoral tissue in 95% patients with testicular germ cell tumors disturbance of spermatogenesis, characteristic for the secretory form of male infertility, are taped. Occurrence of atypical germ cells (TIN) in semen tubules, which were defined in 60% of cases, and overexpressed hyperplasia of Leydig cells of interstition, defined in 82.