Publications by authors named "S V Balalin"
Purpose: To analyze the frequency of main keratotopographic patterns at the 1, 2, and 3 stages of keratoconus and investigate corneal biomechanical properties across different patterns.
Methods: The study comprised two stages. The first stage was computational-experimental, where we utilized COMSOL Multiphysics® software (COMSOL AB, Stockholm, Sweden) to mathematically model corneal mechanical behavior under intraocular pressure and pulsed air jet action in both normal and keratoconic conditions.
Purpose: The study aims to develop a modified personalized topographically and tomographically oriented technique of ultraviolet corneal collagen cross-linking (UVCXL) to affect the area of the cornea with weakest biomechanical properties as determined by mathematical modeling.
Material And Methods: Modeling of the biomechanics of keratoconic cornea under conditions of external diagnostic action was done using COMSOL Multiphysics software. Finite-element analysis procured 3D images of stress/deformation distribution pattern throughout the cornea.
A new compression test with an especially constructed mechanic oculopressor allows to make both functional and tonometric measurements during the test. The method was used in 48 eyes of healthy persons and 196 eyes with advanced, initial glaucoma, preglaucoma and ocular hypertension. The results obtained have shown that the test is effective for detection of preglaucoma and ocular hypertension as well as for differential diagnosis of initial glaucoma and ophthalmic hypertension by the analysis of changes of the blind spot area, the time of restoration of its sizes to the initial state and dynamics of annular compression coefficients at the time of the test.
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