Publications by authors named "S V Avery"
The common cold coronaviruses are a source of ongoing morbidity and mortality particularly among elderly and immunocompromised individuals. While cross-reactive immune responses against multiple coronaviruses have been described following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination, it remains unclear if these confer any degree of cross-protection against the common cold coronaviruses. A recombinant fowl adenovirus vaccine expressing the SARS-CoV-2 spike protein (FAdV-9-S19) was generated, and protection from SARS-CoV-2 challenge was shown in K18-hACE2 mice.
View Article and Find Full Text PDFEurotiales fungi are thought to be distributed worldwide but there is a paucity of information about their occurrence on diverse substrates or hosts and at specific localities. Some of the Eurotiales, including Aspergillus and Penicillium species, produce an array of secondary metabolites of use for agricultural, medicinal, and pharmaceutical applications. Here, we carried out a survey of the Eurotiales in South Korea, focusing on soil, freshwater, and plants (dried persimmon fruits and seeds of Perilla frutescens, known commonly as shiso).
View Article and Find Full Text PDFArticle Synopsis
- Cancer is predicted to rise significantly, with 35 million new cases expected by 2050, mainly impacting low- and middle-income countries, particularly in the SAARC region.
- There is a research investment and output gap in SAARC countries compared to high-income nations, leaving a lack of local studies and clinical trials in crucial areas like targeted therapy and immunotherapy.
- Addressing the challenges of healthcare access, cultural and economic barriers, and limited funding in SAARC countries requires collaboration, improved research infrastructure, and local studies to develop practical and affordable cancer treatments.
Article Synopsis
- - The South Asian region faces a critical shortage of oncology professionals due to inadequate education and training programs, impacting the quality of cancer care.
- - Challenges for oncology workers include lack of trained personnel, poor healthcare infrastructure, and limited educational resources.
- - The paper suggests both short-term strategies to enhance training and long-term goals to create self-sufficient cancer care systems through regional collaboration and innovative education.
Article Synopsis
- Cancer care in SAARC countries faces major challenges like poor infrastructure, lack of skilled professionals, and economic issues, leading to delayed diagnoses and worse health outcomes.
- There are significant disparities in healthcare systems across the region, with some countries providing free public services while others rely heavily on out-of-pocket payments, creating financial inequities for cancer patients.
- To improve cancer care, coordinated efforts are needed, including better infrastructure, expanded health insurance, and national cancer control programs, along with regional collaboration to ensure equitable access and advance health goals.