Publications by authors named "S V Ajay"
Spatial variability in residence time of Beryllium in the Indian Ocean.
J Environ Radioact
December 2024
Residence time of an element in the ocean is a consequence of its chemical behaviour and the various biogeochemical processes governing its distribution, sources, and sinks. Precise estimation of the residence time of beryllium(Be) is necessary for its application as a tracer for understanding present and paleo-environmental processes. We utilise cosmogenic Be and terrestrially derived Be measurements from surface sediments to estimate the residence time of Be in the Indian Ocean.
View Article and Find Full Text PDFThe goal of autotransplantation of teeth (ATT) is to provide the patient with a functioning tooth to replace a missing one. In dentistry, this surgery has gained significant approval and popularity; nonetheless, there is still a shortage of thorough evidence about its long-term effects. Tooth transplantation has a rich historical pedigree, and the main factors determining its success are the extra-alveolar period, proper splinting, periodontal ligament treatment, and root growth stage.
View Article and Find Full Text PDFWhen dealing with a partially edentulous patient requiring rehabilitation for a distal extension, the situation becomes challenging if the patient is unwilling to consider placing implants or using a removable prosthesis. A patient with partial tooth loss may find it difficult to receive a satisfactory repair, especially if the missing teeth are at the back. The surrounding gum tissue and the underlying bone ridges provide support for dentures that encase natural teeth.
View Article and Find Full Text PDFArticle Synopsis
- Clinical genome sequencing (cGS) shows promise in diagnosing rare genetic diseases, especially in underserved populations, with a study examining its effectiveness across high-income and low- and middle-income countries.
- The iHope program assessed 1,004 individuals and found a 41.4% diagnostic yield, with those from low- and middle-income countries being 1.7 times more likely to receive positive results compared to high-income counterparts.
- Over 76% of individuals experienced changes in diagnostic evaluation, and around 41% had changes in management strategies, indicating increased access to genomic testing may help reduce healthcare disparities globally.
Background: Despite monogenic and polygenic contributions to cardiovascular disease (CVD), genetic testing is not widely adopted, and current tests are limited by the breadth of surveyed conditions and interpretation burden.
Methods: We developed a comprehensive clinical genome CVD test with semi-automated interpretation. Monogenic conditions and risk alleles were selected based on the strength of disease association and evidence for increased disease risk, respectively.