Estimating the relative proportions of SARS-CoV-2 haplotypes from wastewater samples.

Wastewater surveillance has become essential for monitoring the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The quantification of SARS-CoV-2 RNA in wastewater correlates with the coronavirus disease 2019 (COVID-19) caseload in a community. However, estimating the proportions of different SARS-CoV-2 haplotypes has remained technically difficult.

Pharmaceutical Composition for Improving Physical Working Capacity.

For development of a pharmaceutical composition improving physical performance, effects of various drugs and their combinations on forced swimming test performance were studied on laboratory rats. Maximum increase in animal performance was produced by a 3-component composition asparcam+mildronate+metaprote in proportion of 5.0, 10.

[The main aspects of the multidisciplinary dispensary dental care to elderly and senile population].

In the article presents the characteristics of the organization of dispensary work with patients older than 60 years. The main directions and objectives dispensary. The features of clinical supervision of dental patients belonging to the category of persons decreed by the elderly, senile age from the perspective of interaction professionals in a multidisciplinary clinic.

Effects of drugs on exercise performance.

The effects of 15 preparations with general tonic, antioxidant, and antihypoxant activities on exercise performance of laboratory rats were studied in the forced swimming test. The best recovery and improvement of exercise performance was recorded after a single intragastric dose of schizandrin and acyzol. These drugs stimulated an increase in the parameters in control animals by 86 and 72% (exercise performance recovery) and by 33 and 51% (exercise performance improvement).

Mechanisms of antioxidant effect of natural sesquiterpene lactone and alkaloid derivatives.

We performed screening of potential antioxidants among natural lactone and alkaloid derivatives and characterized their antioxidant effects. The substances exhibiting antioxidant and metal-chelating potential, in particular, tryptamine derivatives, are promising neuroprotector agents.