[Giant stomach ulcers after selective proximal vagotomy].

On the basis of experimental and clinical investigations the role of vascular microcirculation disorders of gastric wall in pathogenesis of recurrent and peptic ulcers and, in particular, giant ulcers of the stomach after selective proximal vagotomy was established. Giant ulcers of the stomach are considered as trophic or ischemic ulcers, and are shown to be resistant to therapy. Early surgical treatment is recommended.

[Correction of immune disorders in surgery of duodenal ulcer].

The dynamics of immune status in 124 patients operated on for duodenal ulcer are analysed. The patients were divided into two groups: in the study group (60 patients) regional lymphoimmune stimulation with T-activin was used, in patients of the control group T-activin was not used. The depression of immune system in short term period after surgical intervention was detected.

[Vagotomy in the treatment of duodenal ulcer and its complications].

The authors discuss the results of surgical treatment of 577 patients with duodenal ulcer and its complications by operations on the vagus nerve of an isolated character or together with operations on the stomach. The findings of dynamic endoscopic examination of healing of the ulcer in 250 patients are reported. The application of regional lymphostimulation in the prevention and treatment of postvagotomy gastroplegia and gastrostasis in more than 200 patients is described.

[Effect of opioid peptides on the lymphatic drainage of the pancreas in the rat and dog].

The effect of dalargin and some other ligands of the opioid receptors on drainage function of the pancreatic lymphatic system was studied in rats and dogs. In rats, dalargin (30-1000 micrograms/kg, subcutaneously) accelerated the elimination of Evans blue from beneath the pancreatic capsule in a dose-related manner. The effect of dalargin was attenuated by naloxone.