Publications by authors named "S U Bhure"
Among others, methionine residues are highly susceptible to host-generated oxidants. Repair of oxidized methionine (Met-SO) residues to methionine (Met) by methionine sulfoxide reductases (Msrs) play a chief role in stress survival of bacterial pathogens, including Salmonella Typhimurium. Periplasmic proteins, involved in many important cellular functions, are highly susceptible to host-generated oxidants.
View Article and Find Full Text PDFis the principal vector for , , and in animals and the Crimean-Congo hemorrhagic fever virus in humans. Due to the gradual loss of efficacy of the available acaricides against field tick populations, the development of phytoacaricides and vaccines has been considered the two most critical components of the integrated tick management strategies. In the present study, in order to induce both cellular and humoral immune responses in the host against , two multi-epitopic peptides (MEPs), i.
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- The study focuses on creating a multi-target immunization protocol to effectively manage tick infestations in cattle, addressing the challenge of acaricide resistance.
- Researchers evaluated the effectiveness of proteins BM86, subolesin (SUB), and tropomyosin (TPM) for cross-protective potential against various tick species, finding high sequence identity among Indian tick isolates.
- After immunizing cattle with recombinant proteins and measuring antibody responses, the multi-antigen approach showed significant vaccine efficacy of over 86% against different life stages of ticks, supporting the development of a new vaccine strategy.
Article Synopsis
- Buffalo spermatozoa are at risk for cryo-injury due to low antioxidant levels and high polyunsaturated fatty acids, making them susceptible to damage during freezing.
- The study found Humanin present in buffalo spermatozoa and showed that Humanin supplementation, particularly at 5 μM, significantly improved sperm quality post-thaw, reducing lipid peroxidation and enhancing mitochondrial function and DNA integrity.
- Results indicated that Humanin could enhance the fertility potential of buffalo sperm, as evidenced by better kinematics and lower apoptosis in treated samples compared to controls.
To survive and replicate in the host, S. Typhimurium have evolved several metabolic pathways. The glyoxylate shunt is one such pathway that can utilize acetate for the synthesis of glucose and other biomolecules.
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