SETTING AN AGENDA FOR THE APPLICATION OF THE THOUGHT OF ARTHUR SCHOPENHAUER (1788-1860) IN CONTEMPORARY PSYCHIATRY, PSYCHOLOGY, AND PSYCHOTHERAPY.

There is a growing interest in the German thinker Arthur Schopenhauer (1788-1860), sometimes referred to as "the psychologist of the "will", but scarce empirical research has been conducted on the relevance of his philosophy for psychology and psychiatry. Following his death, philosophers, psychologists, psychiatrists, artists, writers, and natural scientists commended him. However, he was harshly criticized by others, notably by Friedrich Nietzsche and Martin Heidegger.

Stereotactic radiotherapy as a valuable therapeutic procedure for controlling aldosterone-secreting adrenocortical carcinoma.

Aldosterone-secreting adrenocortical carcinomas (ACCs) are rare and usually present as large tumors. The only potentially curative treatment for ACC is surgical resection. However, surgery may be unfeasible in some patients who have multiple comorbidities or decline the procedure.

Dermatomyositis: nailfold capillaroscopy patterns and a general survey.

Introduction: Dermatomyositis (DM) is a group of autoimmune idiopathic inflammatory myopathies characterized by typical cutaneous signs and symptoms of muscle involvement. The diseases can be associated with cancer in the paraneoplastic syndrome, calcinosis, interstitial lung disease, other autoimmune connective tissue diseases (in overlap syndrome), and Raynaud's phenomenon.

Methods: Clinical and capillaroscopic data were gathered from 43 patients with DM.

Heptanoate Improves Compensatory Mechanism of Glucose Homeostasis in Mitochondrial Long-Chain Fatty Acid Oxidation Defect.

Defects in mitochondrial fatty acid β-oxidation (FAO) impair metabolic flexibility, which is an essential process for energy homeostasis. Very-long-chain acyl-CoA dehydrogenase (VLCADD; OMIM 609575) deficiency is the most common long-chain mitochondrial FAO disorder presenting with hypoglycemia as a common clinical manifestation. To prevent hypoglycemia, triheptanoin-a triglyceride composed of three heptanoates (C7) esterified with a glycerol backbone-can be used as a dietary treatment, since it is metabolized into precursors for gluconeogenesis.