Long-term outcomes of S-1 and oxaliplatin neoadjuvant chemotherapy with total mesorectal excision and lateral lymph node dissection for rectal cancer.

Purpose: Chemoradiotherapy (CRT) for rectal cancer is limited by its harmful side effects and its insufficient benefit on lateral lymph node metastases. The purpose of this study was to evaluate the long-term outcomes of S-1 and oxaliplatin with total mesorectal excision (TME) and lateral lymph node dissection (LLND) without radiation for rectal cancer.

Methods: The inclusion criteria were patients with stage II or III rectal cancer located within 10 cm from the anal verge.

Frontal nerve schwannoma in a 16-year-old girl presenting with a rapid growth for 2 years.

Background: Orbital schwannomas arising from the frontal nerve are a rare but distinct entity.

Case Description: A 16-year-old girl presented to our hospital with gradually progressive proptosis. Computed tomography (CT) performed 2 years ago incidentally detected a retrobulbar mass in the left orbit measuring 13 mm × 14 mm × 10 mm, which was not identified on CT performed at the age of 4 years.

A unique case of Sylvian arachnoid cyst complicated by chronic subdural hematoma.

Background: Arachnoid cysts (ACs) complicated by chronic subdural hematoma (CSDH) are a rare but distinct entity.

Case Description: A 27-year-old man previously diagnosed with Sylvian AC presented to the hospital with a persistent headache. He was not aware of any preceding head trauma.

Significance of REV7 Expression in p16-Negative Oropharyngeal Squamous Cell Carcinoma.

Background: REV7 is a multifunctional protein involved in various biological processes, including DNA damage response. REV7 expression in human cancer cells influences sensitivity to DNA-damaging agents, and its high expression level is reportedly associated with a poor prognosis in many carcinomas. However, the significance of REV7 expression in human papillomavirus 16-negative oropharyngeal squamous cell carcinoma (OPSCC) remains unclear.

Comparing activity of the gluteus maximus and hamstring muscles in fatigue conditions between hamstring injury-experienced and inexperienced individuals.

Introduction: Muscle fatigue is considered a risk factor for hamstring injury (HSI), which occurs during high-speed running. To decrease this risk, higher gluteal muscle activity may have a role to play. This study aimed to compare the muscle activities of the gluteus maximus (GMax) and hamstring (HS) muscles between HSI-experienced and inexperienced people in pre- and post-fatigue conditions during the swing and stance phases of running.