Interaction Between Early Meals (Big-Breakfast Diet), Clock Gene mRNA Expression, and Gut Microbiome to Regulate Weight Loss and Glucose Metabolism in Obesity and Type 2 Diabetes.

The circadian clock gene system plays a pivotal role in coordinating the daily rhythms of most metabolic processes. It is synchronized with the light-dark cycle and the eating-fasting schedule. Notably, the interaction between meal timing and circadian clock genes (CGs) allows for optimizing metabolic processes at specific times of the day.

Influence of rainfall on size-resolved bioaerosols around a livestock farm.

Bioaerosols, capable of transporting microorganisms, can impact human health and agriculture by spreading to nearby communities. Their transmissions are influenced by various factors, including weather conditions and human activities. However, the scarcity of detailed, taxon-specific data on bioaerosols' sizes limits our ability to assess risks associated with bioaerosols' generation and spread.

Low-Cost Indoor Sensor Deployment for Predicting PM Exposure.

Indoor air quality is critical to human health, as individuals spend an average of 90% of their time indoors. However, indoor particulate matter (PM) sensor networks are not deployed as often as outdoor sensor networks. In this study, indoor PM exposure is investigated via 2 low-cost sensor networks in Pittsburgh.

Circadian clock gene disruption in white blood cells of patients with celiac disease.

Clock gene disruption has been reported in inflammatory and autoimmune diseases. Specifically, it has been shown that clock gene expression is down-regulated in intestinal tissue and peripheral blood mononuclear cells of patients with inflammatory bowel disease (IBD). We aimed to determine the systemic expression of the circadian clock genes in newly diagnosed untreated, young patients with celiac disease (CeD).

Effect of early vs. late time-restricted high-fat feeding on circadian metabolism and weight loss in obese mice.

Time-restricted feeding (TRF) limits the time and duration of food availability without calorie reduction. Although a high-fat (HF) diet leads to disrupted circadian rhythms, TRF can prevent metabolic diseases, emphasizing the importance of the timing component. However, the question of when to implement the feeding window and its metabolic effect remains unclear, specifically in obese and metabolically impaired animals.