Publications by authors named "S Toppo"
Gastrointestinal stromal tumors mimicking as gynecological tumors-A case series.
J Family Med Prim Care
December 2024
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that arise from interstitial cells of Cajal. Due to vague presentation, location and confusing imaging studies, they tend to mimic gynaecological tumors. They usually diagnosed intra-operative and histopathology followed by tumor specific receptors such as KIT, CD34, CD 117 and DOG 1 are mainstay of diagnosis of GIST.
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- Laparoscopic cholecystectomy is the standard treatment for gallbladder stones, but occasionally needs to be converted to open surgery due to intra-operative difficulties, with conversion rates ranging from 1% to 13%.
- A study conducted in India analyzed factors such as age, gender, and ultrasound findings in 93 gallstone patients to predict the likelihood of needing this conversion.
- Key predictors for conversion included the presence of acute cholecystitis, multiple previous gallbladder attacks, and certain ultrasound results indicating a contracted gallbladder.
Article Synopsis
- In developing countries, trauma is a leading cause of death, with increasing vehicle-related injuries prompting the need for effective trauma scoring systems to predict patient outcomes.
- A study conducted at Rajendra Institute of Medical Sciences assessed 204 patients aged over 18 with chest and abdominal trauma, focusing on their care and diagnostic procedures before treatment.
- Results showed a significant male predominance among patients, with automobile accidents being the most common cause of injuries, highlighting the statistical relevance of various trauma scoring systems in predicting mortality and morbidity.
Background Adjuvants have been discovered to prolong the analgesic impact of local anesthetics (LA), while the transversus abdominis plane (TAP) block offers sufficient postoperative pain relief after various abdominal procedures. Nevertheless, the impact of the given LA will determine the duration of the TAP block. Thus, in this investigation, we aimed to estimate the analgesic impact of combining dexmedetomidine (DEX) with levobupivacaine in the TAP block for patients having an infraumbilical incision for an abdominal hysterectomy while under spinal anesthetic.
View Article and Find Full Text PDFDuring the COVID-19 pandemic, immunosuppressed patients showed prolonged SARS-CoV-2 infections, with several studies reporting the accumulation of mutations in the viral genome. The weakened immune system present in these individuals, along with the effect of antiviral therapies, are thought to create a favourable environment for intra-host viral evolution and have been linked to the emergence of new viral variants which strongly challenged containment measures and some therapeutic treatments. To assess whether impaired immunity could lead to the increased instability of viral genomes, longitudinal nasopharyngeal swabs were collected from eight immunocompromised patients and fourteen non-immunocompromised subjects, all undergoing SARS-CoV-2 infection.
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