Publications by authors named "S Topino"
Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure. Right-sided endocarditis, a very uncommon presentation of brucellosis, may be associated with a better prognosis. We describe the case of a 72-year-old woman admitted to our institution with a persistent fever and multiple pulmonary infiltrates.
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- The study explores the effectiveness of noninvasive ventilation (NIV) in adult patients with Acute Respiratory Distress Syndrome (ARDS) caused by COVID-19, revealing a significant rate of NIV failure and mortality risks based on ARDS severity.
- Out of 307 ARDS patients hospitalized, 224 received NIV, with 37.5% experiencing failure, particularly higher in moderate and severe cases compared to mild ARDS.
- The research indicates that starting NIV in mild ARDS patients may enhance its effectiveness and decrease the risk of mortality, suggesting a potential benefit in early intervention for these patients.
Pulmonary thromboembolism (PTE) has been associated with tuberculosis (TB), but the true incidence is unknown. The aim of our study was to retrospectively evaluate the PTE prevalence in TB patients hospitalized at the National Institute for Infectious Diseases L. Spallanzani during the January 2016-December 2021 period.
View Article and Find Full Text PDFIntroduction: The use of steroid therapy in patients within the context of SARS-CoV-2 infection is still a matter of debate. This study aimed to evaluate if potential steroid benefits could be predicted by the ratio of arterial oxygen partial pressure (PaO in mmHg) to fractional inspired oxygen (FiO) (P/F) in COVID-19 patients at admission.
Materials And Methods: Medical records were retrospectively collected from all adult patients admitted because of COVID-19 from 29 January to 31 July 2020.
Background: The WHO advised that the impact of COVID-19 pandemic on TB services was estimated to be dramatic due to the disruption of TB services.
Methods: A retrospective data collection and evaluation was conducted to include all the patients hospitalized for TB at INMI from 9 March to 31 August 2020 (lockdown period and three months thereafter). For the purpose of the study, data from patients hospitalized in the same period of 2019 were also collected.