Publications by authors named "S Toomey"
Objective: To characterize health insurance gap patterns related to age-19 Medicaid and age-26 commercial age-eligibility cutoffs.
Study Setting And Design: This descriptive analysis spans 2014-2018, after Affordable Care Act implementation, but before COVID-19 emergency provisions. We defined insurance gaps as ≥3 consecutive months without observed enrollment, preceded and followed by ≥1 month of enrollment and stratified results by insurance source and clinical severity (e.
The CDK4/6 inhibitor Ribociclib has shown limited efficacy as a monotherapy in colorectal cancer (CRC). However, combining Ribociclib with targeted therapies could present a viable strategy for treating CRC. This study evaluated the combination of Ribociclib and the PI3K inhibitor Alpelisib across four distinct cell lines representing different mutational statuses ( wild-type, -mutated, -mutated, and -mutated).
View Article and Find Full Text PDFArticle Synopsis
- Neoadjuvant radiotherapy is crucial for treating locally advanced rectal cancer, and this study compares the quality-of-life outcomes between two techniques: three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT).
- A phase II randomized trial involved 94 patients who received chemoradiotherapy and were assigned to either 3DCRT or IMRT; their quality of life was assessed using specific questionnaires throughout the treatment and at a six-month follow-up.
- Although the trial ended early due to the futility of its primary endpoint, the results indicated that while emotional functioning improved, other aspects of quality of life declined; notably, IMRT showed better physical and role functioning during the final week
Background: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality in the United States. Frequent exacerbations result in higher use of emergency services and hospitalizations, leading to poor patient outcomes and high costs.
Objective: Demonstrate the feasibility of a multimodal, digitally enhanced remote monitoring, treatment, and tele-pulmonary rehabilitation intervention among patients with COPD.
Article Synopsis
- Chronic obstructive pulmonary disease (COPD) is a prevalent and serious condition, highlighting the need for effective care approaches like pulmonary rehabilitation and early intervention during symptom flare-ups.
- The Healthy at Home study aims to explore a new digital care model for COPD patients over a 6-month period, recruiting 100 participants for its pilot phase.
- Participants will use technology like smartwatches and apps to monitor their symptoms and health data, allowing researchers to gain insights into disease behavior and improve care responses.