Publications by authors named "S Tommasin"
Article Synopsis
- The study investigates how brain lesions causing Alice in Wonderland syndrome (AIWS) relate to a specific brain network involved in size and scale perception, despite lesions appearing in varied regions.
- Researchers analyzed 37 cases of AIWS against a control group of 1,073 lesions from other neuropsychiatric disorders, finding a common connectivity pattern in areas critical for body and size perception.
- The results suggest that AIWS perceptual distortions stem from a shared neural network, which could help in developing future treatments for similar perceptual disorders.
Increasing evidence suggests that the cerebellum may have a role in the pathophysiology of Parkinson's disease (PD). Hence, the scope of this study was to investigate whether there are structural and functional alterations of the cerebellum and whether they correlate with motor and non-motor symptoms in early PD patients. Seventy-six patients with early PD and thirty-one age and sex-matched healthy subjects (HS) were enrolled and underwent a 3 T magnetic resonance imaging (MRI) protocol.
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- Cognitive impairment is prevalent among people with multiple sclerosis (PwMS) and significantly affects their quality of life, making cognitive assessment crucial for treatment and understanding disease progress.
- The study aimed to update normative data for the Brief Repeatable Battery of Neuropsychological Tests (BRB-N) version A in the Italian population by analyzing data from 342 healthy subjects across four Italian sites.
- The results indicate no major demographic differences among the sites, and they established updated z-scores that enhance the reliability of cognitive assessments for PwMS and other clinical groups in Italy.
Article Synopsis
- The study explores the cerebello-thalamo-cortical circuit's role in essential tremor (ET) and examines how various brain abnormalities may relate to a common functional network impacting ET pathophysiology.
- Through a systematic review and coordinate network mapping, researchers identified key brain regions linked to ET, including the cerebellum, thalamus, and motor cortex, as part of a shared and potentially treatable network.
- The cerebellum was highlighted as the core of this network, showing significant differences in connectivity compared to other movement disorders, suggesting its importance in ET treatment strategies.
Dystonia is thought to be a network disorder due to abnormalities in the basal ganglia-thalamo-cortical circuit. We aimed to investigate the white matter (WM) microstructural damage of bundles connecting pre-defined subcortical and cortical regions in cervical dystonia (CD) and blepharospasm (BSP). Thirty-five patients (17 with CD and 18 with BSP) and 17 healthy subjects underwent MRI, including diffusion tensor imaging (DTI).
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