[Correction of Partial Volume Effect Using CT Images in Brain F-FDG PET].

Purpose: We performed partial volume effect correction of PET images using F-FDG-PET and CT images taken consecutively, compared it with correction using MRI images, and investigated the usefulness of correction using CT images.

Methods: A total of 9 clinically normal subjects were included in the study, and the CT and MRI images of each subject were segmented and normalized. PET images were coregistered to each morphological image and then normalized.

Diagnostic Performance of I-FPCIT SPECT Specific Binding Ratio in Progressive Supranuclear Palsy: Use of Core Clinical Features and MRI for Comparison.

Progressive supranuclear palsy (PSP) is listed as a core clinical feature in the Movement Disorder Society 2017 criteria, along with ocular motor dysfunction, postural instability, akinesia, and cognitive dysfunction. Imaging evidence shows predominant mid-brain atrophy and postsynaptic striatal dopaminergic degeneration as two supportive features. The purpose of this study was to investigate the diagnostic performance of I- ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane (I-FP-CIT) SPECT by comparing it with evaluation of core clinical features and MRI in the diagnosis of PSP.

A diagnostic strategy for Lewy body disease using DAT-SPECT, MIBG and Combined index.

Purpose: The functional imaging methods widely used for the diagnosis of Lewy body disease (LBD) are I-N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropan (FP-CIT) with dopamine transporter single photon emission computed tomography (DAT-SPECT) and I-iodobenzylguanidine (MIBG) myocardial scintigraphy. The aim of this study was to determine whether DAT-SPECT or I-MIBG myocardial scintigraphy should be examined first and to evaluate whether the combined use of DAT-SPECT and MIBG myocardial scintigraphy is superior to using either modality alone for diagnosing suspected LBD.

Methods: In this retrospective study, a total of 117 patients suspected of having LBD underwent DAT-SPECT imaging followed by MIBG myocardial scintigraphy.

Clinical usefulness of quantification of myocardial blood flow and flow reserve using CZT-SPECT for detecting coronary artery disease in patients with normal stress perfusion imaging.

Background: Relative myocardial perfusion imaging can misdiagnose "balanced" ischemia caused by coronary artery disease (CAD). We assessed the feasibility of myocardial blood flow (MBF) and myocardial perfusion reserve (MPR) using dynamic single-photon emission computed tomography (SPECT) with a cadmium-zinc-telluride (CZT) camera for estimating underlying CAD in patients with normal stress myocardial perfusion SPECT (MPS).

Methods: 125 patients with normal stress MPS (summed stress score ≤3) were enrolled.

Tc-99m PMT scintigraphy in the diagnosis of pediatric biliary atresia.

Purpose: Hepatobiliary scintigraphy plays an important role in the differentiation of biliary atresia (BA) and non-BA. The usefulness of Tc-iminodiacetic acid (IDA) derivatives in BA diagnosis is reported in several papers. In contrast, there are no comprehensive data on differentiating BA from non-BA using Tc-N-pyridoxyl-5-methyl-tryptophan (PMT).