In medical and health research, investigators are often interested in countable quantities such as hospital length of stay (e.g., in days) or the number of doctor visits.
View Article and Find Full Text PDFHidden Markov models (HMMs) have been extensively used in the univariate and multivariate literature. However, there has been an increased interest in the analysis of matrix-variate data over the recent years. In this manuscript we introduce HMMs for matrix-variate balanced longitudinal data, by assuming a matrix normal distribution in each hidden state.
View Article and Find Full Text PDFA correct modelization of the insurance losses distribution is crucial in the insurance industry. This distribution is generally highly positively skewed, unimodal hump-shaped, and with a heavy right tail. Compound models are a profitable way to accommodate situations in which some of the probability masses are shifted to the tails of the distribution.
View Article and Find Full Text PDFIntroduction: The widespread use of imaging has increased Chiari malformation (CM) diagnosis. CM shows clinical heterogeneity that makes management controversial. We aimed to evaluate the occurrence and clinical and radiographic presentation of children with CM-1 and CM-1.
View Article and Find Full Text PDFBackground: Cirrhosis for biliary atresia (BA) is associated with risk of gastrointestinal bleeding (GB) from gastroesophageal varices due to portal hypertension. Primary prophylaxis of GB is controversial in children who are candidates for liver transplantation (LT). The aim of the study was to define the management of gastroesophageal varices and to identify the benefit of primary prophylaxis for GB in BA children waiting for LT.
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