Publications by authors named "S Tokuyama"
[A long chain fatty acid receptor signaling as a new therapeutic target for stress-induced chronic pain].
Nihon Yakurigaku Zasshi
November 2024
Article Synopsis
- Psychological and social stresses contribute to psychiatric disorders like depression and anxiety, and can also lead to prolonged pain; however, the mechanisms behind stress-induced chronic pain remain complex and poorly understood.
- Research on the GPR40/FFAR1 receptor, which influences insulin secretion in the pancreas, has also revealed its role in regulating pain and emotions in the central nervous system.
- Current investigations are focusing on the signaling pathways of fatty acid receptors in relation to stress-related chronic pain, presenting them as potential new therapeutic targets based on findings from a mouse model that simulates psychosocial stress.
Article Synopsis
- Capicua transcriptional repressor-double homeobox 4 sarcoma (CDS) is a rare and aggressive soft tissue tumor, which in this case was found in the stomach and invaded surrounding organs.
- A 48-year-old male had a large tumor diagnosed initially as neuroendocrine carcinoma, but after extensive imaging and biopsy, it was confirmed as CDS.
- The tumor was successfully removed through a multivisceral resection, and the patient had a good recovery, marking this as the first detailed report of a gastric CDS being surgically managed.
Background: Laugier's hernia is a very rare atypical femoral hernia and is challenging to diagnose preoperatively. Herein, we report a rare case of inguinal and Laugier's hernias treated with laparoscopic transabdominal preperitoneal repair.
Case Presentation: A 63-year-old man was admitted to our hospital with right groin swelling for 4 years.