Publications by authors named "S Togni"
We investigate the role of homeostatic mechanisms involved in acute, postprandial nutrient metabolism and nutrient-induced systemic inflammation in CKD presence and progression in Metabolic dysfunction-associated steatohepatitis (MASH). We assessed postprandial incretins (GLP-1 and GIP), intestinotropic hormone GLP-2, endotoxin LPS, Zonulin (a marker of intestinal permeability), hepatokines, adipokines and NF-kB activation in circulating MNCs during a meal tolerance test in 52 biopsy proven MASH patients randomized to curcumin Meriva or placebo and 26 matched controls. At baseline, MASH-CKD had a lower GLP-2 response and a 2-fold higher postprandial LPS and NF-kB activation in MNCs than MASH patients without CKD, but similar remaining postprandial or fasting parameters.
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- Health services want to understand how patients feel about their care, especially those who speak First Nations languages, to make improvements.
- Researchers worked with language experts and health staff to create surveys that are accurate and meaningful for these patients by translating and testing them.
- They found big challenges in translating survey questions because some English phrases don't mean the same in First Nations languages, and cultural differences also made it hard to ask questions in the right way.
Background: The superiority of early drain removal (EDR) versus late (LDR) after pancreaticoduodenectomy (PD) has been demonstrated only in RCTs.
Methods: A meta-analysis was conducted using a random-effects model and trial sequential analysis. The critical endpoints were morbidity, redrainage, relaparotomy, and postoperative pancreatic fistula (CR-POPF).
Unlabelled: . Preparedness for emergencies: strategies to increase the supply of beds and advanced intensive skills.
Introduction: The recent pandemic has highlighted the importance of emergency preparedness plans.
Quercetin, a natural polyphenol with demonstrated broad-spectrum antiviral, anti-inflammatory, and antioxidant properties, has been proposed as an adjuvant for early-stage coronavirus disease 2019 (COVID-19) infection. To explore the possible therapeutic effect of quercetin in outpatients with early-stage mild to moderate symptoms of COVID-19. This was an open-label randomized controlled clinical trial conducted at the department of medicine, King Edward Medical University, Lahore, PK.
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