Mindfulness-based interventions for substance use disorders.

Background: Substance use disorders (SUDs) are highly prevalent and associated with a substantial public health burden. Although evidence-based interventions exist for treating SUDs, many individuals remain symptomatic despite treatment, and relapse is common.Mindfulness-based interventions (MBIs) have been examined for the treatment of SUDs, but available evidence is mixed.

Meta-analysis of time perception and temporal processing in schizophrenia: Differential effects on precision and accuracy.

Numerous studies have reported that time perception and temporal processing are impaired in schizophrenia. In a meta-analytical review, we differentiate between time perception (judgments of time intervals) and basic temporal processing (e.g.

The interplay of fibronectin functionalization and TGF-β1 presence on fibroblast proliferation, differentiation and migration in 3D matrices.

Defined biomimetic three-dimensional (3D) matrices are needed to decipher the complex cellular signalling during wound healing at high resolution in vitro. Soluble factors like TGF-β1 and adhesion promoting structural components of the extracellular matrix (ECM) are known to be key regulators of fibroblast behaviour. The ECM component fibronectin (FN) bears a complex function as adhesion promoter, fibrillar element and soluble factor binder.