Publications by authors named "S Thiam"
Background: In Africa, the scale-up of malaria-control interventions has reduced malaria burden, but progress towards elimination has stalled. Mass drug administration (MDA) is promising as a transmission-reducing strategy, but evidence from low-to-moderate transmission settings is needed. We aimed to assess the safety, coverage, and effect of three cycles of MDA with dihydroartemisinin-piperaquine plus single, low-dose primaquine on Plasmodium falciparum incidence and prevalence in southeast Senegal.
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- Epidemiological surveillance (ES) is crucial in the fight against malaria, particularly in Senegal's Tambacounda Health District, where it had been previously neglected.
- A survey of 27 health structures revealed that while the ES system was generally accepted by users, issues like low staff training and inadequate data analysis impacted its effectiveness, with only a 25.9% rate of data utilization among managers.
- The system demonstrated strong responsiveness and availability of management tools but requires improvements in staffing and training to enhance its stability and utility in controlling malaria-related morbidity and mortality.
Article Synopsis
- In Senegal, a study evaluated the effectiveness of mass drug administration (MDA) as a strategy to reduce malaria incidence, comparing it to the standard seasonal malaria chemoprevention (SMC) methods.
- The trial was conducted in 60 villages, with one group receiving MDA treatment and the other receiving SMC, both delivered door-to-door.
- Results showed MDA significantly reduced malaria cases by 55% during the peak transmission season, indicating it may be a more effective intervention than standard care without serious side effects reported.
Introduction: Seasonal malaria chemoprevention (SMC) with Sulfadoxine pyrimethamine plus amodiaquine (SP + AQ) consist of a monthly administration of therapeutic dose to children under five years of age during the high risk of malaria in area where malaria is highly seasonal. According to SMC recommendation, both non-infected and asymptomatic infected children will receive similar treatment. The gap in our knowledge is how the effect of asymptomatic infection on the efficacy of SMC in preventing clinical malaria over a four-week period.
View Article and Find Full Text PDFBackground: The sero-epidemiological characteristics of SARS-CoV-2 infections in Mali are not yet well understood. This study assessed SARS-CoV-2 antibody seroprevalence and factors associated with antibody responses in the general population of Bamako, the capital city and epicenter of COVID-19, to assess the magnitude of the pandemic and contribute to control strategy improvements in Mali.
Methods: A cross-sectional survey was conducted in September 2022 to collect sociodemographic information, clinical characteristics, comorbid factors, and blood samples.