Publications by authors named "S Thanigainathan"

Vitamin D deficiency in infants is widely prevalent. Most paediatric professional associations recommend routine vitamin D prophylaxis for infants. However, the optimal dose and duration of supplementation are still debated.

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Objectives: To compare the duration required to regain birth weight following early fortification of human milk vs. late fortification among preterm infants.

Methods: This randomized controlled trial included hemodynamically stable 120 preterm infants (≤32 wk of gestation).

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Article Synopsis
  • Newborns are at higher risk for seizures, which can cause long-term neurodevelopmental issues, but the best treatment options for anti-seizure medications (ASMs) are still being debated.
  • The study aims to evaluate the effectiveness of different ASMs, the need for continued medication after seizure control, and the benefits of treating both clinical and electrographic seizures compared to clinical seizures alone.
  • Researchers conducted comprehensive searches of multiple medical databases for randomized controlled trials to gather data on seizure management in neonates, focusing on their effectiveness and potential long-term outcomes.
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Background: Routine monitoring of gastric residuals in preterm infants on tube feeds is a common practice in neonatal intensive care units used to guide initiation and advancement of enteral feeding. There is a paucity of consensus on whether to re-feed or discard the aspirated gastric residuals. While re-feeding gastric residuals may aid in digestion and promote gastrointestinal motility and maturation by replacing partially digested milk, gastrointestinal enzymes, hormones, and trophic substances, abnormal residuals may result in vomiting, necrotising enterocolitis, or sepsis.

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