Publications by authors named "S Thamizhmaran"
Article Synopsis
- - Noncommunicable diseases, particularly type 2 diabetes, result in 41 million deaths annually and are often undiagnosed, highlighting the need for better detection and management strategies, especially due to the rise in prediabetes cases.
- - The study aimed to determine the prevalence of prediabetes and prehypertension in the rural Puducherry district, involving 203 adults over 30 using community-based methods and various health measurements.
- - Findings indicated that 14.4% were at high risk for diabetes, while hypertension affected 31.3% of participants, with significant links to family history and diet, emphasizing the importance of early detection and lifestyle factors.
Solitary cysticercus granulomas (SCG), prevalent among Indian patients with new-onset seizures, either resolve completely or transform into calcified granulomas. This study aimed to identify serum proteins through liquid chromatography-tandem mass spectrometry that could predict calcification of SCGs in 20 patients with SCG with at least 6-months of follow-up. At a median follow-up of 14 months, the SCG had calcified (n = 5), resolved (n = 11), or persisted (n = 4).
View Article and Find Full Text PDFNeurocysticercosis (NCC), a major cause of global acquired epilepsy, results from Taenia solium larval brain infection. T. solium adult worms release large numbers of infective eggs into the environment contributing to high levels of exposure in endemic areas.
View Article and Find Full Text PDFPrior work has shown that 14 monocyte genes are upregulated in patients with different forms of parenchymal neurocysticercosis, including solitary cysticercus granuloma (SCG). The aim of this study was to investigate whether changes in inflammation associated with SCG seen on follow-up brain imaging are also reflected in changes in expression of these 14 genes. Peripheral blood CD14+ monocytes were isolated from 20 patients with SCG at initial diagnosis and at clinical and imaging follow-up of 6 months or more.
View Article and Find Full Text PDFBackground: In patients with enhancing brain parenchymal lesions, parenchymal neurocysticercosis (pNCC) is often difficult to distinguish from tuberculoma, necessitating biopsy or empirical therapy.
Methods: In a prospective study, peripheral blood monocytes were isolated from patients with definitive pNCC (n = 39) and brain tuberculomas (n = 20). Patients with tuberculomas were diagnosed by the presence of concurrent systemic tuberculosis (n = 7), pathological or bacteriological confirmation (n = 5), and resolution of typical brain lesions following a therapeutic trial of antituberculous therapy (n = 8).