Clinical characteristic and clinical course of aborted sudden cardiac death patients with structurally normal heart in King Chulalongkorn Memorial Hospital.

Background: PED (Primary electrical disease) is an arrhythmogenic disease group that causes serious ventricular tachyarrhythmia in the absence of recognized structural heart disease. Although Thailand, which is a part of Southeast Asia, is an endemic area of PED, especially Brugada syndrome, there is little known about demographic data and clinical outcome of PED among survivors of sudden cardiac death (SCD).

Objective: To study demographic data and clinical outcome of PED among survivors of SCD in Thailand.

Endocardial mapping and catheter ablation for ventricular fibrillation prevention in Brugada syndrome.

Unlabelled: Endocardial Mapping and Ablation of Brugada Syndrome.

Introduction: Brugada syndrome (BS) is characterized by ST-segment elevation in the right precordial electrocardiogram (ECG) leads and episodes of ventricular fibrillation (VF). This study aimed to observe the feasibility of substrate modification by radiofrequency catheter ablation and its effects on VF storm.

Evaluation of acute and subacute oral toxicity of the ethanol extract from Antidesma acidum Retz.

Toxicity tests of 95% ethanol extract of the root of Antidesma acidum were studied in male and female rats. The oral acute toxicity test at 5,000 mg/kg revealed that the ethanol extract did not produce toxic effects on signs, general behavious, mortality and gross appearance of internal organs of rats. Furthermore, the oral sub-acute toxicity test at the dose of 1,000 mg/kg/day displayed no significant changes in body and internal organs' weights, normal hematological and clinical blood chemistry values.

Factors related to volunteer comprehension of informed consent for a clinical trial.

The informed consent process has become a universal requirement for research involving human subjects. Its goal is to inform volunteers regarding research in order to make decision to participate or not. This study aimed to measure volunteers' comprehension levels concerning the clinical trial and to find out factors associated with that comprehension levels.

Acute and subacute toxicity study of the ethanol extract from Lonicera japonica Thunb.

The ethanol extract from the leaves of Lonicera japonica Thunb. was evaluated for acute and subacute toxicity. The single oral dose of the ethanol extract at 5,000 mg/kg did not produce mortality or significant changes in the general behaviour and gross appearance of the internal organs of rats.