Publications by authors named "S Teerenstra"
Objective: The prognostic relevance of hormonal biomarkers in endometrial cancer (EC) has been well-established. A refined three-tiered risk model for estrogen receptor (ER)/progesterone receptor (PR) expression was shown to improve prognostication. This has not been evaluated in relation to the molecular subgroups.
View Article and Find Full Text PDFBackground: Integrating outcome information into the process of shared decision-making (SDM) about post-treatment surveillance can enhance its effectiveness. The Breast Cancer Surveillance Decision Aid (BCS-PtDA) integrates risk estimations of patients' risks for recurrences as well as outcome information on fear of cancer recurrence (FCR). The SHOUT-BC study aimed to evaluate the effectiveness of the implementation of the BCS-PtDA.
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- The study examined the impact of cerebellar anodal transcranial direct current stimulation (tDCS) on cognitive performance among patients suffering from cerebellar cognitive affective syndrome (CCAS), where no established treatment currently exists.
- It involved 35 participants in a randomized, double-blind, sham-controlled trial with assessments of cognitive function, ataxia severity, mood, and quality of life over several months.
- The results showed no significant improvement in cognitive performance from tDCS, but did indicate a noteworthy reduction in ataxia severity, suggesting tDCS may have potential benefits for motor-related symptoms in cerebellar disorders.
Background: High-impact surgery imposes a significant physiological and functional burden and is associated with substantial postoperative morbidity. Multimodal prehabilitation has demonstrated a reduction in postoperative complications and enhanced functional recovery, mainly in abdominal cancer surgery. Common preoperative risk factors shared among patients undergoing high-impact surgery, extending beyond abdominal cancer surgery procedures, suggest the relevance of multimodal prehabilitation to a broader patient population.
View Article and Find Full Text PDFBackground: Hypoglycaemia has been shown to induce a systemic pro-inflammatory response, which may be driven, in part, by the adrenaline response. Prior exposure to hypoglycaemia attenuates counterregulatory hormone responses to subsequent hypoglycaemia, but whether this effect can be extrapolated to the pro-inflammatory response is unclear. Therefore, we investigated the effect of antecedent hypoglycaemia on inflammatory responses to subsequent hypoglycaemia in humans.
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