Publications by authors named "S Taysi"
Introduction: USP9X has been associated with neurodevelopmental disorders due to its role in synaptic development and neural function. This study aimed to compare USP9X and TGF-β levels in children with autism and healthy controls, and explore their relationship with autism severity.
Methods: Serum USP9X and TGF-β levels were measured in 41 healthy control children (aged 3-12 years) and 41 children with autism.
Article Synopsis
- Glycogen synthase kinase 3β (GSK3β) is an enzyme linked to heart failure (HF), and this study examines its serum levels in various HF types.
- Researchers analyzed serum GSK3β levels in 112 HF patients and 50 healthy controls, employing echocardiographic evaluations and statistical analyses to determine significance.
- Results indicated that GSK3β levels were significantly elevated in HF patients compared to controls, with highest levels in heart failure with preserved ejection fraction (HFpEF) and lowest in reduced ejection fraction (HFrEF), suggesting a potential protective mechanism related to ejection fraction.*
Investigation of Nrf2-Keap-1 pathway, Sestrin 2 and oxidative stress markers in serum of patients with placenta Accreata spectrum.
Eur J Obstet Gynecol Reprod Biol
November 2024
Article Synopsis
- Placenta accreta spectrum (PAS) refers to a serious condition where the placenta attaches too deeply into the uterine wall, leading to complications like heavy bleeding and the need for hysterectomies, especially as cesarean rates rise.
- This study focused on the Nrf2-Keap1 signaling pathway in PAS patients, measuring various biomarkers related to oxidative stress and antioxidant activity using the ELISA method.
- The findings indicate significant differences in levels of Nrf2, Keap1, and related markers between PAS patients and a control group, suggesting that the pathway is disrupted in PAS and may help assess the severity of the condition.
Stresses caused by ionizing radiation can also damage tissues and organs through the circulatory system. In this study, we aimed to determine the radioprotective effect of propolis, a natural and powerful antioxidant product, against oxidative liver damage caused by cranial irradiation. Thirty-two male albino Sprague-Dawley rats, divided into four groups, were designed as sham group, irradiation (IR) group, propolis plus IR, control group of propolis.
View Article and Find Full Text PDFObjective: Sodium-glucose co-transporter-2 inhibitors (SGLT-2i) are a new class of drugs that lower blood glucose and reduce mortality in heart failure patients with reduced ejection fraction (HFrEF). They also have antioxidant effects. The exact mechanism of SGLT-2i is unknown.
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