Publications by authors named "S Tavella"

Article Synopsis
  • * New research shows that DNA breaks can actually trigger the production of non-coding RNAs (ncRNAs) that might be essential for signaling and repairing DNA damage.
  • * The study reviews how certain histone modifications are influenced by these ncRNAs, suggesting potential new approaches for targeting DNA repair in therapies.
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  • The European Space Agency (ESA) regularly updates its science plans by talking to scientists about what they need to know.
  • The SSCWP 9 document focuses on "Biology in Space" and discusses important questions that scientists want to answer about how living things adapt to space.
  • One big question is how different organisms change at the molecular level when they are in microgravity, which could help both space missions and new technologies on Earth.
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Introduction: Combined prevention (CP) is considered the key strategy against the HIV epidemic. The objective of the study was to evaluate the perception of risk of HIV infection and the knowledge about the use of antiretrovirals (ARV) for prevention, among patients who attend a Sexually Transmitted Infections (STI) clinic.

Methods: A survey on personal data and perception of risk of HIV infection, knowledge about post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP), was administered to patients at the time of applying doses of penicillin for the treatment of syphilis, or when taking a blood sample for STI diagnosis, between May and December, 2022.

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Progress in mechanobiology allowed us to better understand the important role of mechanical forces in the regulation of biological processes. Space research in the field of life sciences clearly showed that gravity plays a crucial role in biological processes. The space environment offers the unique opportunity to carry out experiments without gravity, helping us not only to understand the effects of gravitational alterations on biological systems but also the mechanisms underlying mechanoperception and cell/tissue response to mechanical and gravitational stresses.

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Article Synopsis
  • The white paper discusses the need for research on how changes in gravity impact animal and human cellular and tissue systems, which is vital for understanding health in space.
  • Current knowledge gaps hinder the development of accurate models to predict long-term health impacts for astronauts during extended missions beyond low Earth orbit.
  • Researchers recommend a more integrated approach to connect biological and physiological effects to better address space adaptation challenges and promote astronaut health during deep space missions.
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