Publications by authors named "S Tarima"
Purpose: Improving locoregional control for breast cancer (BC) results in better overall survival. Contemporary redlining is associated with worse BC survival in older patients. Self-reported race is associated with survival, redlining, and access to care.
View Article and Find Full Text PDFBackground: The SMILE study is a multi-institutional phase II clinical trial to determine the efficacy and safety of an antiprogestin, onapristone, in combination with fulvestrant as second-line therapy for patients with ER+, PgR+/-, HER2- metastatic breast cancer. This study was terminated early and herein, we report patient characteristics, and outcomes.
Methods: Eligibility criteria included disease progression on ≥2 lines of prior therapy, ECOG performance status ≤ 2, measurable disease per RECIST 1.
Article Synopsis
- The study investigates how the timing of hibernation affects retinal damage in 13-lined ground squirrels after injecting them with adenosine triphosphate (ATP).
- Eighteen squirrels were divided into three groups based on the season (early, mid, late) and underwent imaging before and after ATP injection to assess retinal health.
- Results indicated that early-season squirrels were more likely to suffer retinal damage, and further research is suggested to refine ATP dosing based on seasonal ocular changes.
Article Synopsis
- The concept of "quality" in imaging is often influenced by specific fields, and there's a need for a standardized way to assess the quality of photoreceptor images obtained from adaptive optics scanning light ophthalmoscopy (AOSLO).
- This study introduces a new method for evaluating image quality that focuses on calculating the signal to noise ratio (SNR) from 528 images captured by two different AOSLO systems, covering various retinal conditions.
- Results showed that the SNR measurements aligned well with expert ratings, suggesting that this new algorithm offers a reliable and objective way to assess image quality in both healthy and diseased retinas.
Complex musculoskeletal complications in children with hypermobility spectrum disorder (HSD) include pain, proprioception deficits, and joint instability, which may result in movement dysfunction during walking. However, no studies have explored the inter-joint coordination deficits in children with HSD. The purpose of this study was to determine the lower extremity inter-joint coupling angles, patterns, and variability during walking in children with HSD compared to children without HSD (non-HSD).
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