Publications by authors named "S Tano"
Histological chorioamnionitis (HCA) is a form of maternal immune activation (MIA) linked to an increased risk of neurodevelopmental disorders in offspring. Our previous study identified neurodevelopmental impairments in an MIA mouse model mimicking HCA. Thus, this study investigated the role of CD11c microglia, key contributors to myelination through IGF-1 production, in this pathology.
View Article and Find Full Text PDFThe growing recognition of the importance of interpregnancy weight management in reducing hypertensive disorders of pregnancy (HDP) underscores the importance of effective preventive strategies. However, developing effective systems remains a challenge. We aimed to bridge this gap by constructing a prediction model.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to evaluate postpartum follow-up care for women with hypertensive disorders of pregnancy (HDP) in Japan, highlighting its importance for reducing future cardiovascular and metabolic disease risks.
- A web-based survey conducted among postpartum women revealed low awareness of HDP-related risks, with only 56.2% knowing about cardiovascular disease risk and even fewer understanding metabolic syndrome risks or preventive measures.
- The findings indicate that healthcare providers are not adequately informing patients, resulting in a lack of follow-up and awareness, emphasizing the need for better educational resources and follow-up protocols for women after pregnancy.
Background: The accumulation of ascites is a major symptom of ovarian cancer. The volume of ascites is a pathophysiological indicator of the peritoneal environment, such as inflammation and fibrosis; however, the relationship between the volume of ascites and oncological outcomes remains unclear. We herein retrospectively examined the effects of the volume of ascites on the prognosis of epithelial ovarian cancer in a multi-institutional large cohort using the stratification of clinical characteristics and statistical adjustment methods.
View Article and Find Full Text PDFObjective: Assessing the histology-specific prognosis of epithelial ovarian cancer (OvCa) is clinically challenging, especially in a patient population with a favorable prognosis. This study investigated the histology-specific long-term oncologic outcomes in OvCa patients who underwent complete tumor resection using a large-scale patient cohort form multiple institutions under a central pathological review system.
Methods: A regional multi-institutional study was conducted from 1986 to 2019.