Vitamin D Deficiency and Maternal Diseases as Risk Factors for the Development of Macrosomia in Newborns.

The aim is to assess the association between the level of vitamin D, maternal diseases, and macrosomia in newborns. : This study included 258 full-term newborns (86 newborns with macrosomia; and 172 newborns with normal weight). Enzyme immunoassays for the determination of vitamin D were performed.

THE IMPACT OF BIRTH WEIGHT ON INFANT MORTALITY IN KAZAKHSTAN.

Introduction: Recognizing the importance of birth weight is fundamental to addressing public health challenges associated with maternal and child health. Birth weight serves as a critical indicator, offering insights into mortality, stunting, and the development of chronic diseases later in life. This study delves into fertility and infant mortality trends in Kazakhstan, with a specific focus on understanding urban-rural disparities and gender variations in mortality rates.

The role of vitamin D and trace elements in premature newborns with congenital pneumonia.

Objectives: The objective of the research is to determine the levels of vitamin D and trace elements in the umbilical cord blood, as well as to evaluate the clinical and laboratory characteristics in premature newborns with congenital pneumonia.

Materials And Methods: This single‑center case-control research included 228 premature newborns who were divided into the main group composed of 76 newborns with congenital pneumonia, and control group composed of 152 newborns without congenital pneumonia, who were born in the period from January 2021 to December 2021. An enzyme immunoassay of vitamin D determination was performed along with an assessment of clinical and laboratory characteristics.

A modern look at the development of intrauterine pneumonia in premature newborns: Literature review.

Infectious diseases such as malaria, pneumonia, diarrhea and preventable neonatal diseases are common causes of death in children. Globally, neonatal mortality is 44% (2.9 million) annually, with up to 50% of babies dying within the first day of life.

BRCA1 and TP53 Gene-Mutations: Family Predisposition and Radioecological Risk of Developing Breast Cancer.

Frequencies of polymorphisms of genes BRCA1 and TP53 in breast cancer (BC) patients with a BC family history and radiation history were assessed and compared in the Semey region of Kazakhstan. The study included 60 women directly irradiated by the activities of the Semipalatinsk test site with a calculated effective equivalent dose of 500 mSv and their first generation descendants (group BC+Her+Exp); 65 women with family BC and absence of radiological history - the effective equivalent dose due to anthropogenic sources not exceeding 50 mSv (group BC+Her-Exp). The comparison group consisted of 65 women patients with breast cancer without family and radiological history (BC-Her-Exp).