Development of a didactic demonstrator for flow-induced noise mechanisms and mitigation technologies.

A small didactic wind tunnel demonstrator has been designed and manufactured at the von Karman Institute for Fluid Dynamics to illustrate the physical principles at stake in flow-induced noise generation, offer an audible perception of the effectiveness of noise-mitigation strategies, and serve as a practical test bench for aeroacoustic education and research. Seven mitigation technologies are embedded in a single facility, which addresses the noise generation by an airfoil, noise propagation in a duct, and noise transmission through a flexible panel. A challenging objective of this facility was to offer a perceptible impression of various aeroacoustic noise mechanisms at low flow speeds and a live assessment of the effectiveness of noise-reduction technologies.

Second primary malignancies among women with uterine sarcoma.

Objective: Uterine sarcomas (US) are rare malignancies with unclear aetiology. Studies on uterine sarcomas in the setting of second primary malignant tumours can provide clues to aetiology and identify side effects of different treatments.

Methods: A cohort of 8606 cases of US was extracted from the data from 13 cancer registries and followed for second primary cancers within the period 1943-2000.

Second malignancies after childhood noncentral nervous system solid cancer: Results from 13 cancer registries.

Children diagnosed with noncentral nervous system solid cancers (NCNSSC) experience several adverse late effects, including second malignant neoplasm. The aim of our study was to assess the risk of specific second malignancies after a childhood NCNSSC. Diagnosis and follow-up data on 10,988 cases of NCNSSC in children (0-14 years) were obtained from 13 registries.

High constant incidence rates of second primary cancers of the head and neck: a pooled analysis of 13 cancer registries.

Scanty data are available on the incidence (i.e., the absolute risk) of second cancers of the head and neck (HN) and its pattern with age.

Risks of second primary cancer among patients with major histological types of lung cancers in both men and women.

Background: Patterns of second primary cancers (SPCs) following first primary lung cancers (FPLCs) may provide aetiological insights into FPLC.

Methods: Cases of FPLCs in 13 cancer registries in Europe, Australia, Canada, and Singapore were followed up from the date of FPLC diagnosis to the date of SPC diagnosis, date of death, or end of follow-up. Standardised incidence ratios (SIRs) were calculated to estimate the magnitude of SPC development following squamous cell carcinoma (SCC), small cell lung carcinoma (SCLC), and adenocarcinoma (ADC).