Publications by authors named "S Taix"

Background: Primary cutaneous lymphomas (PCLs) are a heterogeneous group of T-cell (CTCL) and B-cell (CBCL) malignancies. Little is known about their epidemiology at initial presentation in Europe and about potential changes over time.

Objectives: The aim of this retrospective study was to analyse the frequency of PCLs in the French Cutaneous Lymphoma Registry (GFELC) and to describe the demography of patients.

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The use of videoconferencing had increased significantly during lockdown. During this period, videoconferencing has been used in the pathological department of pathology (Timone university hospital, Marseille, France) for academic, diagnosis and referral. We provide our point of view regarding the use of this tool.

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Article Synopsis
  • The study aimed to understand the molecular changes that occur as lymphomatoid papulosis (LyP) evolves into cutaneous anaplastic large-cell lymphoma (c-ALCL) and lymph node invasion (LNI).
  • Researchers analyzed nine tumors from a single patient who experienced both LyP and c-ALCL along with other types of lymphoma, finding a common T-cell origin for the CD30+ lesions and a common B-cell origin for diffuse large B-cell lymphoma (DLBCL).
  • They concluded that the evolution from LyP to c-ALCL and LNI represents a progressive clonal evolution from a shared precursor, suggesting that nodal ALCL should be viewed as a transformation rather than a separate entity
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The 5-year survival rate of primary anorectal malignant melanoma is less than 20%. Optimal treatment of this condition remains controversial regarding locally disease, and whether any preferential survival benefit arises from either abdominoperineal resection or wide local excision remains unknown. The majority of patients progress to metastatic disease, and for decades, the use of chemotherapies, such as platines or dacarbazine, has been advocated to improve overall survival.

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