Publications by authors named "S Tais"
Background: Strongyloidiasis is a chronic parasitic disease that results in relevant human morbidity, caused by the nematode Strongyloides stercoralis. This nematode has a unique and complex life-cycle. There is so far no perfect test for this helminthiasis.
View Article and Find Full Text PDFBackground: Currently approved vaccines are highly effective in protecting against hospitalization and severe COVID-19 infections. How pre-existing immunity responds to new variants with mutated antigens is crucial information for elucidating the functional interplay between antibodies and B and T cell responses during infection with new SARS-CoV-2 variants.
Methods: In this study, we monitored the dynamics and persistence of the immune response versus different SARS-CoV-2 variants of concern that emerged during the pandemic period (2021-2022) in a cohort of vaccinated healthcare workers, who experienced breakthrough infection in the Pre-Delta, Delta, and Omicron waves.
Some serology assays demonstrated useful for post-treatment monitoring of infection. Serology frequently has low specificity, which might be improved by the use of recombinant antigens. The Strongy Detect ELISA is based on 2 recombinant antigens (SsIR and NIE) and proved good accuracy.
View Article and Find Full Text PDFIntroduction: Cancer patients are at risk for serious complications in case of SARS-CoV-2 infection. In these patients SARS-CoV-2 vaccination is strongly recommended, with the preferential use of mRNA vaccines. The antibody response in cancer patients is variable, depending on the type of cancer and antitumoral treatment.
View Article and Find Full Text PDFArticle Synopsis
- Screening for neglected tropical diseases like Chagas disease and strongyloidiasis is not common among HIV-positive migrants from Latin America living in Italy.
- A study evaluated 389 HIV-infected migrants, finding that about 3.86% tested positive for Chagas disease, with varying prevalence based on the confirmatory techniques used, and 4.11% tested positive for strongyloidiasis.
- The study highlights the uncertainty in the accuracy of tests for these infections and suggests that better diagnostic strategies should be implemented for patients with unclear test results to prevent serious health issues.