Improvements in exercise tolerance with an exercise intensity above the anaerobic threshold in patients with acute myocardial infarction.

Anaerobic threshold (AT) from cardiopulmonary exercise tests (CPX) is the standard for measuring exercise intensity among patients with cardiovascular disease in Japan. However, it remains controversial whether AT represents the safety limit for exercise intensity in patients with cardiovascular disease. The purpose of this study was to investigate cardiac rehabilitation (CR) efficacy and safety with exercise intensities above the AT and at a traditional AT in a randomized trial.

MuCHLoc: Indoor ZigBee Localization System Utilizing Inter-Channel Characteristics.

The deployment of a large-scale indoor sensor network faces a sensor localization problem because we need to manually locate significantly large numbers of sensors when Global Positioning System (GPS) is unavailable in an indoor environment. Fingerprinting localization is a popular indoor localization method relying on the received signal strength (RSS) of radio signals, which helps to solve the sensor localization problem. However, fingerprinting suffers from low accuracy because of an RSS instability, particularly in sensor localization, owing to low-power ZigBee modules used on sensor nodes.

Danger-Pose Detection System Using Commodity Wi-Fi for Bathroom Monitoring.

A bathroom has higher probability of accidents than other rooms due to a slippery floor and temperature change. Because of high privacy and humidity, we face difficulties in monitoring inside a bathroom using traditional healthcare methods based on cameras and wearable sensors. In this paper, we present a danger-pose detection system using commodity Wi-Fi devices, which can be applied to bathroom monitoring, preserving privacy.

Phase 1/2 study of the WT1 peptide cancer vaccine WT4869 in patients with myelodysplastic syndrome.

WT4869 is a synthetic peptide vaccine derived from the Wilms' tumor gene 1 (WT1) protein. This phase 1/2 open-label study evaluated the safety and efficacy of WT4869, and biomarkers for response, in patients with myelodysplastic syndrome. WT4869 (5-1200 μg/dose) was administered intradermally every 2 weeks, according to a 3 + 3 dose-escalation method in higher-risk (International Prognostic Scoring System score ≥1.

Toe grip strength in middle-aged individuals as a risk factor for falls.

Background: Toe grip strength is the force of a toe on a surface. The objective of this study was to investigate the relationship between falls in middle-aged individuals and physical strength factors such as toe grip strength and knee extension strength.

Methods: The subjects were 194 middle-aged individuals (388 feet) who were independent in daily life, received no nursing care, and participated in a health sports event organized by a sports club.