Publications by authors named "S T Oommen"

Background: Methicillin-resistant (MRSA) is a significant burden globally, particularly in the Arabian Gulf region. The United Arab Emirates (UAE) has experienced rising MRSA prevalence, with increasing diversity in the clonal complexes (CCs) identified. The COVID-19 pandemic, with its increased hospitalization rates and antibiotic use, may have further influenced MRSA's genetic evolution and epidemiology in the country.

View Article and Find Full Text PDF

Purpose: The present study evaluated the dosimetric impact and compared the dose variations between the advanced collapsed cone engine (Task Group 186) and Task Group 43 plans for cervical cancer using tandem and ovoid applicators.

Material And Methods: Thirty cervical cancer patients underwent iridium-192 (Ir) high-dose-rate (HDR) intra-cavitary brachytherapy using tandem and ovoid applicator. Original treatment plans for all patients were created using TG-43 dose calculation formalism.

View Article and Find Full Text PDF

Introduction: The Alsin Rho Guanine Nucleotide Exchange Factor ( gene encodes a protein alsin that functions as a guanine nucleotide exchange factor. The variations in gene leads to degeneration of upper motor neurons of the corticospinal tract. The phenotypes resulting from variants in gene are infantile-onset ascending hereditary spastic paralysis (IAHSP, OMIM # 607225), juvenile primary lateral sclerosis (JPLS, OMIM # 606353), and juvenile amyotrophic lateral sclerosis (JALS, OMIM # 205100).

View Article and Find Full Text PDF

Introduction The COVID-19 pandemic has overwhelmingly affected healthcare systems, particularly in the area of antibiotic management. The surge in antimicrobial use to address secondary bacterial infections in COVID-19 patients has heightened concerns about overuse and antimicrobial resistance (AMR). This study examined the pandemic's effect on the antibiotic stewardship program (ASP) at two general hospitals in Abu Dhabi, focusing on changes in prescribing practices, adherence to stewardship guidelines, resistance trends, and overall health system impact.

View Article and Find Full Text PDF
Article Synopsis
  • The COVID-19 pandemic emphasizes the necessity for resilient healthcare systems, especially regarding antibiotic stewardship in hospitals like those in Abu Dhabi.
  • This study evaluates the maturity levels of antibiotic stewardship programs in a general hospital by analyzing prescribing practices and the hospital's readiness for managing infectious disease outbreaks from data on non-surgical patients aged 25-40.
  • Findings from the study of 240 cases indicated key insights into antibiotic usage patterns, including an average treatment duration and instances of duplicate therapy, which will help improve antibiotic management during health crises.
View Article and Find Full Text PDF