Publications by authors named "S T Okino"

Background: Underdoses of direct oral anticoagulants (DOAC) are sometimes prescribed due to bleeding risk concerns in patients with atrial fibrillation (AF). We investigated the prevalence of DOAC underdosing and its impact on clinical outcomes in AF patients undergoing percutaneous coronary intervention (PCI).

Methods And Results: This multicenter observational cohort study enrolled patients with AF on DOAC undergoing PCI between January 2015 and March 2021 at 15 institutions across Japan.

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Article Synopsis
  • Left ventricular (LV) pseudoaneurysm is a rare but serious complication that can occur after a heart attack or heart surgery, often manifesting years later, as seen in the case of an 83-year-old man who developed it 18 years post-Dor operation.
  • The patient experienced rapid heart enlargement and dyspnea, which was diagnosed as an LV pseudoaneurysm through various non-invasive imaging techniques, revealing that the suture connecting the patch to the heart muscle weakened over time.
  • Although surgery is typically recommended due to the high risk of rupture, the patient was not a suitable candidate due to age and renal issues, so he was treated conservatively with medication for hypertension and heart failure.
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Background: This study aims to assess the safety of coronary artery bypass grafting (CABG) with percutaneous ventricular assist device (PVAD) in patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS).

Methods: A retrospective analysis was conducted on 1198 patients with AMI-CS from the J-PVAD registry, who underwent PVAD support using Impella® (Abiomed Inc., Danvers, MA) and subsequent revascularization between February 2020 and December 2021.

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Article Synopsis
  • - The study investigated how body mass index (BMI) influences bleeding and cardiovascular events in patients with atrial fibrillation (AF) taking oral anticoagulants (OAC) after undergoing percutaneous coronary intervention (PCI) for coronary artery disease (CAD).
  • - Conducted in Japan, it involved 720 patients divided into two BMI groups: those with BMI <21.3 kg/m² and those with BMI ≥21.3 kg/m², revealing significantly higher rates of net adverse clinical events (NACE) and major adverse cardiovascular events (MACE) in the lower BMI group.
  • - The findings suggest that a BMI <21.3 kg/m² is a key predictor for increased NACE and MACE in
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Background: Coronary spastic angina (CSA) in premenopausal women is not frequent but has also been suggested to be associated with oestrogen decline during the menstrual cycle and sometimes becomes refractory and difficult to control. We experienced two premenopausal women with CSA that showed the involvement of the menstrual cycle.

Case Summary: Case 1: 41-year-old-woman had ST-segment elevation and chest pain during urosepsis, just 2 days after the onset of menstruation.

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