Synthesis of waterborne polyurethane-carboxymethyl chitosan cross-linked biodegradable bio-based porous materials for the adsorption of methylene blue.

The development of green and cost-effective biomass adsorbents is necessary for removing large amounts of dyes from wastewater. In this study, polyurethane prepolymers were synthesized using polycaprolactone diol (OH-PCL-OH), isophorone diisocyanate, and 2,2-dihydroxymethylpropionic acid, which were subsequently dispersed in aqueous carboxymethyl chitosan (CMCS) solution to produce waterborne polyurethane (WPU)-CMCS porous materials. The adsorbent was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectrometer (FT-IR), thermogravimetric (TGA) and mercury intrusion porosimetry (MIP).

Dual-OR Logic-Gated Lateral Flow Strip Assay Based on Colorimetric-Fluorescence Dual Indication for Screening of HPV16/18 in Multiple Scenarios.

The incidence of cervical cancer continues to rise in underdeveloped regions due to low human papillomavirus (HPV) vaccination rates and inadequate screening systems. To achieve convenient, rapid, and accurate detection of HPV, we developed a three-wire lateral flow strip assay system based on dual-OR logic gates for rapid and simultaneous detection of HPV subtypes 16 and 18 in a single test. The system combines three-branch-catalytic hairpin assembly (TCHA)-mediated signal amplification with simple OR logic gate-based signal output to improve detection rates while enabling HPV 16/18 subtype identification.

Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals.

Imprinting abnormalities pose a significant challenge in applications involving embryonic stem cells, induced pluripotent stem cells, and animal cloning, with no universal correction method owing to their complexity and stochastic nature. In this study, we targeted these defects at their source-embryos from same-sex parents-aiming to establish a stable, maintainable imprinting pattern de novo in mammalian cells. Using bi-paternal mouse embryos, which exhibit severe imprinting defects and are typically non-viable, we introduced frameshift mutations, gene deletions, and regulatory edits at 20 key imprinted loci, ultimately achieving the development of fully adult animals, albeit with a relatively low survival rate.

Transport dynamics of photo-induced carriers in GaN quantum well infrared photodetectors influenced by triangular potentials.

The intrinsic spontaneous and piezoelectric polarizations of GaN lead to the formation of triangular wells and barriers, resulting in the manifestation of chaotic transport models in GaN quantum well intersubband transition (ISBT) infrared detectors and giving rise to various adverse effects. The APSYS software was utilized to construct a novel GaN quantum well ISBT infrared detector in this study. By endeavoring to modify the quantum well structure, our objective was to precisely adjust the energy level of the first excited state (E1) to align with the apex of the triangular barrier.