Publications by authors named "S T M Duong"
The emergence of metallo-β-lactamase (MBL)-producing Enterobacterales presents unique clinical treatment challenges. Recently developed β-lactam/ β-lactamase inhibitor combination agents, while effective against other carbapenemase-producing organisms, are notably ineffective against MBL producers. While MBLs do not hydrolyze monobactams (aztreonam), many MBL-producing organisms are resistant to aztreonam through alternate mechanisms, leaving cefiderocol as the sole monotherapy treatment option recommended for MBL producers.
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- Increased intracranial pressure (ICP) ≥15 mmHg can harm neurological health, but measuring it traditionally requires invasive methods; researchers developed a new AI-based biomarker (aICP) using non-invasive extracranial waveform data instead.
- The aICP was validated using an independent dataset and showed good performance metrics with an area under the receiver operating characteristic curve (AUROC) of 0.80 and an accuracy of 73.8%.
- Further analysis indicated that higher aICP predictions are linked to specific health conditions, such as brain tumors and intracerebral hemorrhages, suggesting its potential clinical relevance.
Background: In patients with congenitally corrected transposition of the great arteries (ccTGA), assessment of readiness for the double switch operation (DSO) after pulmonary arterial band (PAB) placement involves cardiac magnetic resonance imaging (cMRI) to measure left ventricular ejection fraction (LVEF) and mass and cardiac catheterization (catheterization) to assess the ratio of left ventricular to right ventricular pressure (LV:RVp). The aims of this study were to describe the relationships between echocardiographic and catheterization and cMRI measures of readiness for DSO and to develop risk factors for left ventricular (LV) dysfunction after DSO on the basis of echocardiographic measures of ventricular-arterial coupling (VAC).
Methods: Patients with ccTGA undergoing LV retraining at a DSO referral center were reviewed.