Publications by authors named "S T C Peake"
Background: Limited literature exists on nutrition practices for long-stay patients in the intensive care unit (ICU). We aimed to compare nutrition practices in the first and second weeks of an ICU admission.
Method: A post hoc exploratory analysis of The Augmented vs Routine Approach to Giving Energy Trial (TARGET) randomized controlled trial (RCT) was undertaken.
Article Synopsis
- Critically ill patients in Australia and New Zealand often don't meet energy and protein targets with oral nutrition, especially compared to those who start enteral or parenteral nutrition in ICU.
- The study analyzed data from 409 patients across 44 hospitals to compare outcomes, focusing on energy delivery and nutrition assessment during hospital stays.
- Results showed that patients on oral nutrition had lower energy and protein intake, fewer invasive interventions, and received less nutrition assessment compared to those who switched to enteral or parenteral nutrition.
Article Synopsis
- Despite previous trials, it's still unclear how to effectively resuscitate patients with septic shock, prompting a deeper look into individual differences in treatment responses.
- The study utilized machine learning to predict individual patient risk differences and evaluate how their characteristics affected treatment effectiveness across two large cohorts.
- Results indicated significant variability in treatment responses; patients predicted to have the highest risks improved with early goal-directed therapy (EGDT), while those at lower risk potentially faced harm from the same treatment.
Article Synopsis
- Critically ill patients with traumatic brain injury (TBI) may face extended ICU stays, but the effect of increased enteral nutrition energy delivery on their quality of life is unclear.
- This study aimed to compare the quality of life of TBI survivors on an augmented energy diet (1.5 kcal/ml) versus a routine diet (1.0 kcal/ml) at six months post-admission, while also examining energy delivery, gastrointestinal tolerance, and mortality outcomes.
- Results showed no significant difference in quality of life between the two groups, though those on augmented nutrition received more energy without increased gastrointestinal issues.