Publications by authors named "S T Abdurrahman"
Article Synopsis
- * Research suggests that henna plant's phenolic compounds, particularly luteolin, can act as an anti-diabetic agent by inhibiting the α-amylase enzyme, which is crucial for sugar digestion.
- * Molecular studies revealed that luteolin shows strong binding interactions with α-amylase and α-glucosidase, indicating its potential effectiveness in diabetes treatment, with favorable characteristics for absorption and stability in the body. *
Mycobacterium tuberculosis and HIV constitute a public health challenge. Health workers (HWs) in HIV clinics maybe at greater risk of M. tuberculosis infection, considering the high rates of HIV/tuberculosis (TB) coinfection among patients.
View Article and Find Full Text PDFAlopecia is a condition in which hair on the scalp or other areas of the body is lost or falls out excessively. Nutritional deficiency causes blood flow to the head to decrease causing the hormone testosterone to be changed by the enzyme 5-α-reductase to dihydrotestosterone, which inhibits the growth phase and accelerates the death phase. One of the methods developed to treat alopecia is through inhibition of the 5-α-reductase enzyme, which converts testosterone to its more potent metabolite, dihydrotestosterone (DHT).
View Article and Find Full Text PDFArticle Synopsis
- Alopecia is a condition characterized by hair loss due to a mix of genetic, environmental, and nutritional factors, with treatments targeting the enzyme 5-alpha reductase to block the formation of a potent hormone linked to hair loss.
- An in vivo study on rabbits tested the antialopecia effects of ethanolic extracts from a specific plant, revealing that certain fractions (F2 and F3) significantly promoted hair growth, outperforming a control treatment (minoxidil).
- Analysis identified bufotalinin, a compound from the plant, as a strong potential treatment due to its effective binding to androgen receptors and favorable absorption properties, suggesting it could serve as an alternative therapy for hair loss.
The target for COVID-19 has been successfully crystallized along with its inhibitor, named SARS-CoV-2 main protease, making it easier for drug discovery and development. Sponge ( Sp.) is a marine species that can be found in Indonesia and has a unique chemical structure that is still rarely explored in its properties.
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