Publications by authors named "S Suryanti"
Renal cell carcinoma occurrence is increasing from time to time and known as one of the most common cancers worldwide. RCC usually found in older age and common acquired risk factors for RCC including obesity, hypertension, diabetes, smoking and long-term use of NSAIDs. As for genetic risk, it is noted that Von Hippel-Lindau gene involved in the pathogenesis of RCC.
View Article and Find Full Text PDFThe global pandemic of COVID-19 caused by SARS-CoV-2 has caused more than 400 million infections with more than 5.7 million deaths worldwide, and the number of validated therapies from natural products for treating coronavirus infections needs to be increased. Therefore, the virtual screening of bioactive compounds from natural products based on computational methods could be an interesting strategy.
View Article and Find Full Text PDFIntroduction: Rac1 and Galectin-3 has been suggested to involve in the invasion and aggressive behaviour of several cancers. The aim of this study is to evaluate the immunoreactivity of Rac1 and Galectin-3 in follicular adenoma (FA) and follicular thyroid carcinoma (FC) in an attempt to investigate its association with the invasion of FC and its immunohistochemical diagnostic value to discriminate FA and FC.
Materials And Methods: This study included 120 selected paraffin embedded tissue blocks from surgically resected follicular thyroid neoplasms, consists of 60 cases of FA and 60 cases of FC.
CD103+ T Lymphocyte Count Linked to the Thickness of Invasion on Acral Melanoma without E-Cadherin Involvement.
Clin Cosmet Investig Dermatol
November 2021
Article Synopsis
- - Acral melanoma (AM) is an aggressive skin cancer found in areas of the body that don't get sun exposure, and E-cadherin and CD103 are both markers related to its invasion and progression, though E-cadherin's role in AM is not well understood.
- - This research aimed to examine the relationship between E-cadherin and CD103 immunoexpression and the thickness of invasion in 40 AM tissue samples, using a Chi-Square test to analyze the data.
- - Results showed no significant link between E-cadherin and invasion thickness (p = 0.4272), while CD103 exhibited a significant association (p = 0.0001), suggesting that CD103 might
Article Synopsis
- Clear cell renal cell carcinoma (ccRCC) is a highly lethal urinary tract cancer that is resistant to standard treatments, with a low survival rate when metastasis occurs.
- The study focuses on the role of cyclooxygenase-2 (COX-2), an inflammatory protein, and programmed death ligand-1 (PD-L1) in the metastasis of ccRCC.
- Results indicate a significant link between high COX-2 levels and increased metastases, while PD-L1 levels had no significant association with metastasis or with COX-2 expression.