Publications by authors named "S Sue"
Amoebic colitis is a parasitic gastrointestinal disease caused by Entamoeba histolytica (E. histolytica). In Japan, metronidazole (MNZ) monotherapy is often used and most cases are effective.
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- * Twenty patients who had failed previous eradication therapies participated in the study, and the treatment lasted for 14 days, which was adjusted by removing any resistant drugs identified in prior tests.
- * The resulting eradication rates were 63.2% in overall analysis and 70.6% when strictly adhering to the protocol, suggesting this modified therapy could be an effective option after other treatments have failed, with no serious side effects reported.
Risk factors for unclear margin in cold snare polypectomy for colorectal polyp.
Eur J Gastroenterol Hepatol
December 2024
Article Synopsis
- Cold snare polypectomy (CSP) is a commonly used, safe procedure for removing colorectal polyps, but it often results in unclear margins, which can complicate diagnosis and treatment decisions.
- A study analyzed 572 polyps from 237 patients, finding that 41.4% had unclear margins, particularly at anatomical challenging areas (straddling folds, flexure points) and when performed by trainees.
- The findings suggest that as trainees gain more experience, the rate of unclear margins may decrease, improving the safety and efficacy of CSP over time.
Background: Most ovarian cancer cases are diagnosed at an advanced stage, leading to poor outcomes and a relatively low 5-year survival rate. While tumor resection in the early stages can be highly effective, recurrence following primary treatment remains a significant cause of mortality. Propofol is a commonly used intravenous anesthetic agent in cancer resection surgery.
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- Observational studies utilizing real-world data (real-world evidence) are increasingly being integrated into drug development and policymaking, highlighting the importance of a solid quality management system for accurate data collection.
- Our study on a specific intractable disease employed a comprehensive risk-based quality management approach to assess and mitigate potential risks associated with this real-world data analysis.
- We concluded that using a risk-based framework is not only feasible but essential in ensuring the validity of outcomes and the quality of databases in observational studies, ultimately leading to more reliable real-world evidence.