Publications by authors named "S Sudharsana"
White spot disease caused by white spot syndrome virus (WSSV) is a lethal disease for shrimp. Envelope structural proteins play a major role in viral attachment and are believed to be the initial molecules to interact with the host cell. Thus, the envelope proteins have been preferred as a potential molecular target for drug discovery.
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- WSSV is a significant virus affecting shrimp and crustacean farming in Asia, leading to major economic losses.
- The envelope proteins VP26 and VP28 are critical for the virus’s infection process and require further research for effective antiviral therapies.
- A novel compound, 3-(1-chloropiperidin-4-yl)-6-fluoro benzisoxazole 2, shows promising antiviral activity against WSSV, validated through studies in freshwater crabs and in silico molecular docking analyses.
Human subcutaneous dirofilariasis is a rare helminthic infection. It is caused by filarial worms of the Genus Dirofilaria, which is the natural parasites of dogs, cats, foxes, and wild mammals. Zoonotic filariasis caused by Dirofilaria species is rarely seen in the region of Dakshina Kannada.
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