Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis - a pilot randomized controlled trial.

Background: Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage people in physical activity and disease management.

Congenital cystic adenomatoid malformation type 0-a rare cause of neonatal death.

Objective: We give the first account of failure of extracorporeal membrane oxygenation therapy secondary to congenital cystic malformation of the lung (CCAM) type 0.

Design: Case report.

Setting: Pediatric intensive care unit.

Anomalous Dispersion with Edges in the Soft X-ray Region: First Results of Diffraction from Single Crystals of Trypsin Near the K-Absorption Edge of Sulfur.

Anomalous dispersion of X-ray diffraction at wavelengths near the X-ray K-absorption edge of sulfur at wavelengths around 5 A has been applied to single crystals of trypsin obtained from an ammonium sulfate solution. The multiwavelength anomalous-dispersion method based on 775 unique reflections (+183 Bijvoet mates) measured at three wavelengths near the K-absorption edge of sulfur in trypsin (two methionines and disulfide bridges of six cystines) reproduces the known features of the trypsin structure of a resolution of 4 A. It appears that there is anisotropic anomalous scattering from the disulfide bridges of cystine.

Anomalous Dispersion with Edges in the Soft X-ray Region: First Results of Diffraction from Single Crystals of Ribosomes Near the K-Absorption Edge of Phosphorus.

X-ray diffraction from a single crystal of the small ribosomal subunit of Thermus thermophilus was measured at five wavelengths near the K-absorption edge of phosphorus. The intensity of the low-order diffraction peaks varies strongly with the wavelength. It is influenced by the dispersion of contrast due to the P atoms of the ribosomal ribonucleic acid and by that of absorption, in comparable amounts.