Radioisotopic detection of sentinel lymph nodes in clinically localized high-risk prostate cancer.

Purpose: To explore the efficacy of a radioisotopic (RI) method in detecting sentinel lymph nodes (SLNs), known as sites of harboring metastases, in localized high-risk prostate cancer (HRPC).

Methods: The RI method was applied to 26 males with clinically localized HRPC, subjected to radical prostatectomy in 2006-2008. All had poor pathological characteristics: initial PSA > 15 ng/ml, Gleason score > 7, clinically suspected extracapsular extension, seminal vesicle invasion, and/or positive pelvic lymph nodes (LNs).

[Local screening program for prostate cancer].

Objective: By massive screening of men between 50 and 75 years of age, to find those of them that are in the early stage of the carcinoma of the prostate and evaluate the usefulness of applying this method nationwide.

Patients And Methods: 183 male Pleven citizens between 50 and 75 years of age underwent clinical examination, digital rectal examination (DRE) and serum prostate-specific antigen (PSA) determination. Those with suspicious DRE or PSA > 4 ng/ml underwent further examinations: transrectal ultrasonography (TRUS) and biopsy.

[Treatment of benign prostatic hyperplasia with tamsulosin].

The past few decades mark a rejuvenation of the contingent of benign prostate hyperplasia (BPH) patients. The condition affects mainly the active age in men, with the substantial financial burden of treatment leading to a surge of interest in the disease. The hazards of postoperative complications development constrain modern urologists to seek for new, safer and more effective methods of conservative management.

[A paraneoplastic syndrome in patients with a carcinoma of the upper urinary tract].

Evidence of a paraneoplastic syndrome is established in 21/63 patients (33.3 per cent) presenting upper urinary tract tumors. It becomes manifest 2-5 months before diagnosing the basic malignant disease.