Comparing Cancer Primary and Secondary Prevention Documentation Between Different Digital Health Approaches in the Emergency Department.

Background: Decreasing primary care access and increasing emergency department (ED) usage is a potential contributor to declining cancer screening prevalences in those facing barriers to health care access. The ED is a non-traditional yet potentially high-yield setting for implementation of interventions to monitor and increase cancer screening.

Methods: An ED-administered survey in July 2022 gathered data on breast, cervical, and colorectal cancer screening, as well as human papillomavirus (HPV) vaccination status of females presenting to the ED for care.

Emergency Department Visits Before Cancer Diagnosis Among Women at Mayo Clinic.

Objective: To determine associations of incident cancer diagnoses in women with recent emergency department (ED) care.

Patients And Methods: A retrospective cohort study analyzing biological females aged 18 years and older, who were diagnosed with an incident primary cancer (12 cancer types studied) from January 1, 2015, to December 31, 2021, from electronic health records. The primary outcome was a cancer diagnosis within 6 months of a preceding ED visit.

Dual-Energy Computed Tomography Has Additional Prognostic Value Over Clinical Measures in Gout Including Tophi: A Systematic Literature Review.

Objective: This systematic literature review determined whether there is clinical utility for dual-energy computed tomography (DECT) to inform on prognosis for patients with gout. With DECT, individualized treatment plans could be developed based on the patient's unique urate burden, with DECT being used as a clinical outcome measure in gout management.

Methods: To evaluate DECT as a reliable, valid, and sensitive prognostic instrument, a librarian-assisted search was undertaken in PubMed and Embase for articles on gout and DECT informing on reliability; content, construct, and criterion validity; sensitivity to change; and minimum clinically important changes.

Preclinical and clinical characterization of the cutaneous bioavailability of the hydrophilic phase of a water-in-oil emulsion.

Background: Interactions between the stratum corneum and individual phases of an emulsion system depend on various factors, but primarily on the outer continuous phase of the system. While there is plenty of data on the lipophilic phase, only very little data exists on the actual penetration of the hydrophilic phase of water-in-oil emulsions into the stratum corneum.

Patients And Methods: Against this background, two comparable water-in-oil emulsions were preclinically and clinically investigated on healthy as well as on artificially damaged skin with regard to interactions of the hydrophilic phase.

Thioarsenates in sulfidic waters.

It has long been recognized that the formation of soluble arsenic sulfur complexes plays a key role for the mobility and toxicity of arsenic in sulfate-reducing environments. Knowledge of the exact arsenic species is essential to understand the behavior of arsenic in sulfidic aquifers and to develop remediation strategies. In the past, monomeric and trimeric thioarsenites were assumed to be the existing species in sulfidic systems.