Chromosome 22q11 deletions, velo-cardio-facial syndrome and early-onset psychosis. Molecular genetic study.

Background: Velo-cardio-facial syndrome (VCFS) is associated with interstitial deletions of chromosome 22q11. About 30% of patients with VCFS have psychosis, and the rate of these deletions in schizophrenia has been reported to be about 1%. Even higher rates of VCFS deletions have been reported for childhood-onset schizophrenia.

[The motivation for deciding on keeping or terminating a pregnancy. II. The socioeconomic factors, the self-assessment of health status and the attitude towards the future].

Subject of investigation are peculiarities of emotional and motivational sphere of women in a fertile age (women recently confined or terminating pregnancy by wish). They are divided according to their attitude towards real pregnancy. Results of investigation show that double-pole attitude towards pregnancy is in direct dependence on the employment, on the security of working place.

[The motivation for deciding to preserve or to terminate a pregnancy].

With 68 women recently confined and terminating pregnancy by wish a study was made about anxiety in its two varieties: (i) as a mental condition connected with an actual and significant for the person life situation and (ii) as a personal feature--a way of perception and interpretation of the events as threatening. Anxiety's level is measured by a psychological test adapted to the Bulgarian conditions. The high average estimation of anxiety shows that termination of pregnancy is suffered as a stress.

[The results of a study of frustration and depression in older primiparae].

On the basis of an experimental group of 40 elder nulliparous women (ENP) (over 35 years of age) and a control group of 70 nulliparous women, aged up to 30 years of age, and examined at the chair of obstetrics and gynecology in the town of Pleven, the authors investigated the psychic state of women under the conditions of frustration and searched for hidden or manifest depression. Picture-frustration test of C. Rosenzweig and self-evaluating scale of A.