Constructs across a hierarchical, dimensional model of psychopathology show differential associations with social and general cognitive ability.

Many psychiatric disorders and associated psychopathology dimensions are related to social cognitive deficits and reduced general cognitive ability. The current study applied a hierarchical, dimensional approach to better understand associations among psychopathology, social cognition, and general cognitive ability. Data were collected from two samples (n = 653), including psychosis-spectrum patients, their first-degree relatives, and individuals from community sources.

Error monitoring and response inhibition in adolescents with bipolar disorders: An ERP study.

Cognitive control develops throughout adolescence, a high-risk period for bipolar disorders (BD) onset. Despite neurobehavioral abnormalities in adults with BD, there is minimal research investigating deviations in cognitive control in adolescents with BD. Cognitive control involves numerous processes.

Impaired contour object perception in psychosis.

Background: Contour integration, the process of joining spatially separated elements into a single unified line, has consistently been found to be impaired in schizophrenia. Recent work suggests that this deficit could be associated with psychotic symptomatology, rather than a specific diagnosis such as schizophrenia.

Methods: Examining a transdiagnostic sample of participants with psychotic psychopathology, we obtained quantitative indices of contour perception in a psychophysical behavioral task.

Orientation-dependent contextual modulation of contrast in schizophrenia.

Introduction: Schizophrenia is associated with weakened contextual modulation of visual contrast perception, which is generally predicted by population average neural firing rates in primary visual cortex (V1). We use high field fMRI and a novel task to assess V1-instrinsic and V1-extrinsic mechanisms of atypical contextual modulation in schizophrenia.

Methods: We examined the BOLD responses of individuals with schizophrenia (SCZ = 34), bipolar disorder (BP = 25), unaffected first-degree relatives of SCZ (SREL = 20), unaffected first-degree relatives of BP (BPREL = 13) and healthy controls (CON = 23).

Generalized Slowing of Resting-State Neural Oscillations in People With Schizophrenia.

Background: Recent interest in how neural oscillations reflect the flow of information through the brain has led to partitioning electroencephalography (EEG) recordings into periodic (i.e., oscillatory) and aperiodic (i.