Publications by authors named "S Spencker"

Article Synopsis
  • * Given the link between Clostridium septicum and colorectal cancer, a colonoscopy was conducted, resulting in the identification and removal of an adenocarcinoma.
  • * Five months later, the patient experienced severe symptoms, and a CT scan showed a mycotic aneurysm in the aorta, prompting a conservative treatment approach due to his delicate health condition.
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Acute rheumatic fever (ARF) results from an autoimmune reaction following Streptococcus pyogenes-induced tonsilitis. It is a disease that has become uncommon in Germany and is rare in adults. Treatment recommendations are controversial in this age group.

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Cardiac implantable electronic device (CIED)-related infections are a major complication of CIED therapy and associated with high morbidity and mortality. The aim of the present study was to evaluate the incidence of lead erosion as one cause of the CIED-related infections and to provide detailed information about the therapy of two cases of lead erosion. We retrospectively screened the database of a large clinic specialized on patients with CIED (HIZ BERLIN Herzschrittmacher- und ICD-Zentrum, Berlin, Germany) for cases of lead erosion between 2015 and 2020.

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Takotsubo cardiomyopathy has potentially lethal complications and can be caused by a media-induced diffuse atmosphere of life threatening and panic in preconditioned patients.

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Article Synopsis
  • The study investigated the genetic factors related to sudden cardiac death (SCD), focusing on specific gene variations in patients with implantable cardioverter-defibrillators (ICDs).
  • In the DISCOVERY trial, seven single-nucleotide polymorphisms (SNPs) in genes related to G-proteins were analyzed, revealing significant associations of two SNPs in the GNAS gene with ventricular tachyarrhythmia (VT).
  • These findings were further validated in a larger community-based group, showing that the identified SNPs may predict increased risks for both VT and SCD.
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